Childhood Brain Tumors

Çocukluk Çağı Beyin Tümörleri
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Çocukluk Çağı Beyin Tümörleri

Childhood Brain Tumors

Types of Childhood Brain Tumors

Childhood brain tumors, while rarer than those seen in adults, can affect children of any age. These tumors come in various subtypes, and treatment approaches largely depend on the type of tumor.

Types of Childhood Brain Tumors

  • Astrocytomas: Especially pilocytic astrocytomas, are among the most common types of childhood brain tumors and are generally considered benign.
  • Medulloblastomas: Arise in the brainstem, particularly in a region called the posterior fossa. These tumors are malignant and can grow rapidly.
  • Ependymomas: Can appear in the brain ventricles (spaces within the brain) and the spinal cord canal.
  • Craniopharyngiomas: Found near the hypothalamus and pituitary gland. They are usually benign.
  • Supratentorial Astroblastomas: A rare type of tumor that occurs in the upper part of the brain.
  • Atypical Teratoid Rhabdoid Tumors (AT/RT): Rare and difficult to treat tumors.

Differences Between Childhood and Adult Brain Tumors

  • Tumor Types: Childhood brain tumors tend to have different types compared to those found in adults. For example, medulloblastomas are more common in children, whereas glioblastomas are more frequent in adults.
  • Genetic and Molecular Differences: Particularly medulloblastomas can have unique genetic and molecular characteristics, affecting treatment options and prognosis.
  • Brain Development and Growth: Tumors can develop while children’s brains are still developing, influencing treatment approaches and their effects.
  • Symptoms and Diagnosis: Behavior changes or headaches are common symptoms in children. The diagnostic process may vary based on these symptoms.
  • Treatment Tolerance: Children may be more sensitive to chemotherapy and radiation, necessitating treatment plans tailored to their age and the type of tumor.
  • Prognosis: Some childhood brain tumors may have a better prognosis compared to their adult counterparts. For instance, pilocytic astrocytomas are often considered benign.

Symptoms

  • Headache
  • Balance problems
  • Blurred vision
  • Vomiting
  • Behavior changes
  • Neurological issues

Diagnosis

Childhood brain tumors are diagnosed through neurological examinations, imaging studies (MRI or CT scans), and sometimes biopsy.

Treatment

Treatment varies based on the type and stage of the tumor. Options include surgery, radiation therapy, and chemotherapy. The treatment plan is determined by factors such as the child’s age, tumor location and size, genetic factors, and other considerations.

Prognosis

Early diagnosis and appropriate treatment can improve recovery chances for many children with brain tumors. However, prognosis can vary depending on the type and stage of the tumor.

Rehabilitation and Follow-Up

Post-treatment rehabilitation and regular follow-up are crucial for monitoring the child’s health and development. Minimizing post-treatment effects and supporting the child’s long-term health and quality of life are essential.

The treatment process for childhood brain tumors should be managed with a multidisciplinary approach involving pediatric neurology and oncology specialists. The treatment plan should be designed to address the child’s physical and psychological needs.

Frequently Asked Questions​

Childhood brain tumors are the second most common type of cancer in children. Approximately 5 out of every 100,000 children are diagnosed with a brain tumor each year.

Symptoms depend on the location and size of the tumor. Common symptoms include headaches that worsen in the morning, nausea and vomiting, vision problems, balance issues, seizures, behavioral changes, and developmental delays.

Diagnosis typically involves a neurological examination, magnetic resonance imaging (MRI), computed tomography (CT), and biopsy. Cerebrospinal fluid analysis can also aid in diagnosis.

Treatment options include surgery, radiation therapy, chemotherapy, and clinical trials. The treatment plan is determined based on factors such as the type and location of the tumor and the patient’s overall health.